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Semi-retired Michigan lawyer Paul Biegler takes the case of Army Lt. Manion, who murdered a local innkeeper after his wife claimed that he raped her. Over the course of an extensive trial, Biegler parries with District Attorney Lodwick and out-of-town prosecutor Claude Dancer to set his client free, but his case rests on the victim's mysterious business partner, who's hiding a dark secret.

James Stewart
Paul "Pauly" Biegler

Lee Remick
Laura Manion

Ben Gazzara
Lieutenant Frederick "Manny" Manion

Arthur O'Connell
Parnell Emmett "Parn" McCarthy

Eve Arden
Maida Rutledge

Kathryn Grant
Mary Pilant

George C. Scott
AAG Claude Dancer

Orson Bean
Dr. Matthew Smith

Russ Brown
Deputy Sheriff George Lemon

Murray Hamilton
Alphonse "Al" Paquette

Brooks West
DA Mitchell "Mitch" Lodwick

Ken Lynch
Det. Sgt. James "Jim" Durgo

John Qualen
Deputy Sheriff Sulo Kangas

Howard McNear
Dr. Adelord Dompierre

Alexander Campbell
Dr. W. Gregory Harcourt

Ned Wever
Dr. Homer Raschid

Jimmy Conlin
Clarence "One-Shot" "Smoky" Madigan

Royal Beal
Sheriff Max Battisfore

Joseph Kearns
Lloyd Burke

Don Ross
Duane "Duke" Miller

Lloyd Le Vasseur
Court clerk

James Waters
Army Sergeant 1st Class

Joseph N. Welch
Judge Harlan Weaver

Duke Ellington
Pie Eye (uncredited)

Irv Kupcinet
Distinguished Gentleman (uncredited)

Chuck Ramsay
Orderly (uncredited)

Agnes Rodgers Brown
Juror (uncredited)