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Hapless driving instructor and former Gunnery Sergeant Rafferty, living in squalor near Hollywood, California, doesn't put up too much of a fight when two ladies hitch a ride and attempt to kidnap him in their attempt to get to New Orleans; while initially put off, Rafferty finds he's charmed by the kooky pair of misfits and the three of them drive to Las Vegas, Nevada and later Tucson, Arizona, where their bond eventually unravels.
Alan Arkin
Rafferty
Sally Kellerman
Mac
Mackenzie Phillips
Frisbee
Alex Rocco
Vinnie
Charles Martin Smith
Alan Boone
Harry Dean Stanton
Billy Winston
George O'Hanlon, Jr.
Roy - Gas Station Attendant
Barbara Colby
Young Woman
John McLiam
John Beechwood
Richard Hale
Reverend Culpepper
Louis Prima
Himself
Sam Butera
Sam Butera
Arch Johnson
Smitty
David Proval
The Incessant Talker
Ed Peck
Mr. Big Time
Cliff Emmich
Cliff Wilson - Used Car Dealer
Lillian Randolph
Elderly Woman Driver
Margarita García
Lady at Used Car Lot
Ted Gehring
Gas Station Owner
Gus Peters
Man on Street
Norman Jacobs
Dealer
Max David Schiffman
Man in Restaurant
Walter Scott
Policeman
Charles M. Mulkern
Plumbing Salesman
Earl W. Smith
Johnny Young
Emmett Brown
Browny
Mable Matlen
Nun
Clark L. Paylow
Fred
Rosemary Throckmorton
Mary
Don Ames
Man at Slots (uncredited)
Steve DeFrance
Car Driver (uncredited)
Kimiko Hiroshige
Mrs. Chang (uncredited)
Tom Willett
Pedestrian (uncredited)